Harry Isted, Panuchte Camará and Tayo Edun will make their first competitive starts as Charlton players in this evening’s first round Carabao Cup tie at Newport County.
The trio joined the club this summer and fellow new signing Terry Taylor is on the bench for the first time.
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Lucas Ness retains his place in the starting XI from Saturday as Dean Holden makes 10 changes from the team that beat Leyton Orient 1-0.
Ness will be joined in a back three by fellow academy graduate Zach Mitchell and captain Michael Hector in front of Isted.
Richard Chin and Edun are expected to operate as wing-backs with Conor McGrandles and Jack Payne joining Camará in midfield, behind a front two of Daniel Kanu and Charlie Kirk.
Taylor is joined on the bench by Ashley Maynard-Brewer, Mandela Egbo, Terell Thomas, George Dobson, Karoy Anderson, Corey Blackett-Taylor, Tyreece Campbell and Alfie May.
Charlton: Isted; Mitchell, Ness, Hector (c); Chin, McGrandles, Payne, Camará, Edun; Kanu, Kirk
Substitutes: Maynard-Brewer, Egbo, Thomas, Dobson, Taylor, Anderson, Blackett-Taylor, Campbell, May