Connor Wickham will make his first start for the Addicks in this afternoon's game against Cambridge United.
Tyreeq Bakinson and Tyreece Campbell also start as Nathan Jones makes three changes from the team that drew with Wigan Athletic in midweek.
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With the versatility in the starting line-up, the Addicks could remain in a 3-5-2 formation or adopt a diamond formation. If the aforementioned, Terell Thomas, Michael Hector and Gillesphey would once again start in a back three in front Harry Isted.
Karoy Anderson may operate as a right wing-back with Thierry Small as left wing-back.
Conor Coventry, captain George Dobson and Bakinson could play as a midfield three with Wickham and Campbell up front.
January signing Lewis Ward comes on to the bench in place of Ashley Maynard-Brewer with Kayne Ramsay, Rarmani Edmonds-Green, Tayo Edun, Kazenga LuaLua, Alfie May and Chuks Aneke also potential gamechangers for Jones.
Charlton: Isted; Thomas, Hector, Gillesphey; Anderson, Coventry, Dobson (c), Bakinson, Small; Wickham, Campbell
Subs: Ward, Ramsay, Edmonds-Green, Edun, LuaLua, May, Aneke
