Josh Magennis is a major doubt for Charlton after he limped out of Tuesday evening's victory over Scunthorpe United.
The Addicks will definitely be without Jake Forster-Caskey (hamstring) and Chris Solly (calf), but Jordan Botaka could be back in contention after being sidelined on Tuesday.
Long-term absentee Jason Pearce will also miss out, but is set to return to action for the U23s in their Premier League Cup clash with AFC Wimbledon on Sunday.
Charlton and Walsall have met on 31 previous occasions with the Addicks coming out on top 15 times with, and the Saddlers claiming 10 wins, while the remaining six fixtures have ended in draws.
The last meeting saw Charlton come away from the Bescot Stadium with a 2-1 victory last August, while Walsall's last visit to SE7 came in April 2012, with Danny N'Guessan scoring the only goal in a 1-0 victory for the hosts.
Walsall Manager Jon Whitney: ““It’s nice we’re going to Charlton on the back of two wins. We’ve been really solid but I think now, with where we are at the moment, we can try and go and see if the home teams can stop us scoring goals.”
Charlton Manager Karl Robinson: Walsall, like us, had a game on Tuesday, so it will be difficult for both teams. They are sitting outside the playoffs as well, so it will be a challenge but we’re in a false position with the talent this club possesses, we’re a match for anybody as we showed on Tuesday.”
Walsall Manager Jon Whitney: ““It’s nice we’re going to Charlton on the back of two wins. We’ve been really solid but I think now, with where we are at the moment, we can try and go and see if the home teams can stop us scoring goals.”
Nicholas Kinseley takes charge of Saturday's clash with Walsall at The Valley.
The referee has taken charge of 24 games so far this season, brandishing 99 yellow cards and six red.
His last experience of being the man in the middle in SE7 was during the 1-1 draw with Oldham Athletic in September - the only game this season in which he has been able to keep his cards in his pocket this season.
Supporters can follow all the build-up to the game on Charlton's official Instagram account, official Twitter account, Facebook page, official Snapchat account and on the CAFC Wall.
Live commentary of the clash will be available on the club’s Matchday Live service on CAFC PlayerHD.
Supporters can follow live updates and have your say by using the CAFC Wall. An in-depth match report and full match reaction will be available shortly after the final whistle, while supporters can watch extended, multi-angle highlights on CAFC PlayerHD.
Tickets for Saturday’s match remain on sale. It has been classified as an Addicks silver game and ticket prices start at £17 adults, £14 adult disabled, £13 over 65s, £10 students, disabled concessions and U18s, and £5 U11s.
Tickets for the match can be purchased in person from the Valley Superstore, from the Ticket Office on the night of the game, by calling 03330 14 44 44 or by going online. Please click here to visit our ticketing website.