Pape Souaré and Diallang Jaiyesimi both start this afternoon’s Sky Bet League One encounter at Plymouth Argyle (3pm) as manager Johnnie Jackson makes two enforced changes.
The duo replace Akin Famewo and Conor Washington who, along with Josh Davison, have returned positive tests for COVID-19.
Elsewhere, Ryan Inniss returns to the matchday squad for the first time in almost four months, with Nathan Harness, Chris Gunter and Mason Burstow also named on the bench.
Craig MacGillivray continues in goal, with Sean Clare and Ben Purrington expected to operate either side of club captain Jason Pearce.
The returning Jaiyesimi and Souaré are likely to occupy wing-back roles with Alex Gilbey, George Dobson and Elliot Lee manning an unchanged midfield, behind a front two of Leko and Jayden Stockley.
Harness, Gunter, Inniss and Burstow are joined on the bench by Ben Watson, Albie Morgan and Charlie Kirk.
Charlton: MacGillivray; Clare, Pearce (c), Souaré; Jaiyesimi, Gilbey, Dobson, Lee, Purrington; Leko, Stockley
Subs: Harness, Gunter, Inniss, Watson, Morgan, Kirk, Burstow
Supporters in the UK and Ireland can listen to live commentary of the game on CharltonTV, with BBC London Sport’s Jamie Reid joining Addicks legend Steve Brown in the gantry. Click here to purchase your pass.
Supporters based outside of the UK and Ireland can purchase a live streaming pass for this afternoon’s game by clicking here, with former Addicks forward Garry Nelson starring alongside Alan Curbishley and host Scott Minto in the CharltonTV studio, presented by DNEL Ltd.